Jobs
PhD student in immunology / tumor immunology

Deadline:
open until filled
Area:
Medical Sciences, Cancer research, Immunology
Institution:
University of Berne
Location:
Berne, Switzerland

Starting date: July - September 2018 (negotiable)
Application deadline: 30.06.2018

Job description:

Background and tasks

A PhD student position supported among others by the Swiss Cancer League is available for the project “Role of IL-33 signaling for immunopathology and cancer”.
Interleukin-33 (IL-33) is a member of the IL-1 family of cytokines that is released upon tissue damage to operate as an “alarmin”. IL-33 has so far been mainly involved in allergy, yet there is cumulating evidence that it also plays an important role during cancer. In this project, we will use mouse models to study the role of IL-33 signaling in blood cancer and solid tumors. We will also investigate how IL-33 triggers immune cell function during inflammatory disease.

To evaluate the clinical relevance of the findings generated in the mouse models, we will perform translational studies using specimens from human patients with the corresponding disease or cancer.

Technologies utilized in this project include immunological and molecular biology techniques, cell culture, fluorescence microscopy, and histology.
This project will provide multiple opportunities for collaborations and scientific exchange. The candidate will have access to state-of-the-art scientific equipment and core facilities.

Literatur:

Wasmer MH, Krebs P, Front Immunol. 2017 Jan 9;7:682. doi: 10.3389
Mertz KD et al, Oncoimmunology. 2015 Jun 26;5(1):e1062966
Mager LF et al, J Clin Invest. 2015 Jul 1;125(7):2579-91. doi: 10.1172

Requirements:

We are looking for a strongly motivated and talented candidate with a Masters Degree in life sciences or biomedical sciences (Bologna compatible).

The ideal candidate should have a solid background in immunology and cellular biology, and ideally be familiar with common immunology techniques including flow cytometry. Previous experience with murine models represents an advantage but is not a prerequisite. The candidate should be proactive, have good communication skills (in English) and possess an aptitude to work in a team as well as independently. Only applicants with outstanding CVs and references can be considered for this position.

If your profile matches our requirements, we look forward to receiving your application. The single PDF file should include: CV, copies of diplomas and transcripts, a brief statement of your specific qualification for this position and the names and telephone numbers of two references.

We offer:

Our group offers a well-funded research project in a young and dynamic environment. The Institute of Pathology provides an attractive research setting that enables cutting-edge basic research together with facilitated access to human specimens and clinical data.
Bern, the capital of Switzerland, is located very close to the Swiss Alps and is well connected to many important European cities (Milan, Zurich, Paris, and Munich). The salary will be according to the guidelines of the Swiss National Science Foundation: http://www.snf.ch/en/funding/documents-downloads/Pages/default.aspx#Regulations (see Annex 12).

Contact:

Universität Bern
Institut für Pathologie
Philippe Krebs, PhD
Murtenstrasse 31
CH-3008 Bern
Tel. +41 31 632 49 71
Email: philippe.krebs@pathology.unibe.ch

Institut für Pathologie / Experimentelle Pathologie / Immunpathologie, Murtenstrasse 31, 3008 Bern
www.pathology.unibe.ch/research/researchgroups/groupkrebs/index_eng.html

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